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28846-1-AP targets Phospho-ASK1 (Ser966) in WB, ELISA applications and shows reactivity with Human, Mouse samples.
| Tested Applications | WB, ELISA |
| Cited Applications | WB |
| Tested Reactivity | Human, Mouse |
| Cited Reactivity | Human, Mouse, Rat |
| Immunogen | Peptide 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | mitogen-activated protein kinase kinase kinase 5 |
| Synonyms | ASK 1, ASK1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5, Phospho-ASK1 (Ser966) |
| Calculated molecular weight | 155 kDa |
| Observed molecular weight | 120 kDa |
| GenBank accession number | BC054503 |
| Gene symbol | MAP3K5 |
| Uniprot | Q99683 |
| Gene ID (NCBI) | 4217 |
| RRID | AB_2881220 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species (ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase (JNK) and p38. The predicted MW of ASK1 is around 155 kDa and the 110-120 kDa fragment has also been reported.
| PRODUCT SPECIFIC PROTOCOLS | |
|---|---|
| WB protocol for Phospho-ASK1 (Ser966) antibody 28846-1-AP | Download protocol |
| STANDARD PROTOCOLS | |
|---|---|
| Click here to view our Standard Protocols |
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